Article
Molecular origin of the L-type Ca2+ current of skeletal muscle myotubes selectively deficient in dihydropyridine receptor beta1a subunit.
Biophysical journal - 1 Jul 1998
Strube C, Beurg M, Sukhareva M, Ahern C A, Powell J A, Powers P A, Gregg R G, Coronado R
Abstract excerpt
The origin of Ibetanull, the Ca2+ current of myotubes from mice lacking the skeletal dihydropyridine receptor (DHPR) beta1a subunit, was investigated. The density of Ibetanull was similar to that of Idys, the Ca2+ current of myotubes from dysgenic mice lacking the skeletal DHPR alpha1S subunit (-...
Topics
- Animals
- Biophysical Phenomena
- Biophysics
- Calcium
- Calcium Channels
- Calcium Channels, L-Type
- Cells, Cultured
- Ion Channel Gating
- Kinetics
- Membrane Potentials
- Mice
- Muscle, Skeletal
- Mutation