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Article

Divalent cations permeation in a Ca2+ non-conducting skeletal muscle dihydropyridine receptor mouse model.

Cell calcium - 1 Nov 2020

Idoux Romane, Fuster Clarisse, Jacquemond Vincent, Dayal Anamika, Grabner Manfred, Charnet Pierre, Allard Bruno

Abstract excerpt

In response to excitation of skeletal muscle fibers, trains of action potentials induce changes in the configuration of the dihydropyridine receptor (DHPR) anchored in the tubular membrane which opens the Ca2+ release channel in the sarcoplasmic reticulum membrane. The DHPR also functions as a voltage-gated Ca2+ channel that conducts L-type Ca2+ currents routinely recorded in mammalian muscle fibers, which role...

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Source

Identifiers

PMID: 32866694
DOI: 10.1016/j.ceca.2020.102256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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