Article
Ca2+ sparks in embryonic mouse skeletal muscle selectively deficient in dihydropyridine receptor alpha1S or beta1a subunits.
Biophysical journal - 1 Feb 1999
Conklin M W, Powers P, Gregg R G, Coronado R
Abstract excerpt
Ca2+ sparks are miniature Ca2+ release events from the sarcoplasmic reticulum of muscle cells. We examined the kinetics of Ca2+ sparks in excitation-contraction uncoupled myotubes from mouse embryos lacking the beta1 subunit and mdg embryos lacking the alpha1S subunit of the dihydropyridine recep...
Topics
- Animals
- Caffeine
- Calcium
- Calcium Channels
- Calcium Channels, L-Type
- Cells, Cultured
- Image Processing, Computer-Assisted
- Kinetics
- Mice
- Mice, Knockout
- Microscopy, Fluorescence
- Muscle, Skeletal
- Mutation
- Ryanodine Receptor Calcium Release Channel
- Tetracaine