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Reactive Oxygen Species Modulate Anopheles gambiae Immunity against Bacteria and Plasmodium

7 Dec 2007

Abstract excerpt

The involvement of reactive oxygen species (ROS) in mosquito immunity against bacteria and Plasmodium was investigated in the malaria vector Anopheles gambiae. Strains of An. gambiae with higher systemic levels of ROS survive a bacterial challenge better, whereas reduction of ROS by dietary administration of antioxidants significantly decreases survival, indicating that ROS are required to mount effective...

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PMID: 18065421
DOI: 10.1074/jbc.m705873200

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