Article
Effect of thioredoxin peroxidase-1 gene disruption on the liver stages of the rodent malaria parasite Plasmodium berghei.
Parasitology international - 1 Jun 2015
Usui Miho, Masuda-Suganuma Hirono, Fukumoto Shinya, Angeles Jose Ma M, Hakimi Hassan, Inoue Noboru, Kawazu Shin-Ichiro
Abstract excerpt
Phenotypic observation of thioredoxin peroxidase-1 (TPx-1) gene-disrupted Plasmodium berghei (TPx-1 KO) in the liver-stage was performed with an in vitro infection system in order to investigate defective liver-stage development in a mouse infection model. Indirect immunofluorescence microscopy assay with anti-circumsporozoite protein antibody revealed that in the liver schizont stage, TPx-1 KO parasite cells...
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