Article
C/EBPbeta activates E2F-regulated genes in vivo via recruitment of the coactivator CREB-binding protein/P300.
The Journal of biological chemistry - 24 Aug 2007
Wang Haitao, Larris Brian, Peiris T Harshani, Zhang Liping, Le Lay John, Gao Yan, Greenbaum Linda E
Abstract excerpt
The E2F transcription factors play an essential role in regulating the G(1)- to S-phase transition of the cell cycle. Previous studies have identified the importance of interactions between E2Fs and other transcription factors as a mechanism for transcriptional control of a subset of E2F regulated target genes. However, the mechanisms responsible for E2F target gene specificity remain incompletely understood....
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