Article
X‐ray structures of Sap1 and Sap5: Structural comparison of the secreted aspartic proteinases from <i>Candida albicans</i>
2 Apr 2008
Abstract excerpt
Proteolytic activity is an important virulence factor for Candida albicans (C. albicans). It is attributed to the family of the secreted aspartic proteinases (Saps) from C. albicans with a minimum of 10 members. Saps show controlled expression and regulation for the individual stages of the infection process. Distinct isoenzymes can be responsible for adherence and tissue damage of local infections, while others...
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