[What functions do six different genes for secretory proteinases have in Candida albicans?].

doi:10.1111/j.1439-0507.1998.tb00583.x

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Article

[What functions do six different genes for secretory proteinases have in Candida albicans?].

Mycoses - 1 Jan 1998

Hube B, Sanglard D, Schaller M, Ibrahim A, Odds F C, Gow N A

Abstract excerpt

Secreted Aspartate Proteinases (Sap) are among those factors of the human pathogen Candida albicans, which promote infections in the immunocompromised host. Sap isoenzymes are encoded by at least nine different genes (SAP1-9), which are differentially regulated in vitro. RT-PCR analysis during ex...

Topics

Candida albicans
Candidiasis
Endopeptidases
Gene Expression Regulation, Fungal
Humans
Hydrolysis
Isoenzymes
Membrane Proteins
Multigene Family
Mutation
Polymerase Chain Reaction
Virulence

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