Article
Underground metabolism.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Feb 1998
D'Ari R, Casadesús J
Abstract excerpt
All enzymes are able to use alternative substrates. When these are naturally occurring metabolites, an 'underground reaction' takes place. Examples are presented in which underground metabolism of this sort produces an observable phenotype. Although biological processes can be remarkably accurate, evolution has selected error rates far from perfect. It is suggested here that a certain level of metabolic...
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