Article
Mannan-binding lectin in human serum, cerebrospinal fluid and brain tissue and its role in Alzheimer's disease.
Neuroreport - 11 May 1998
Lanzrein A S, Jobst K A, Thiel S, Jensenius J C, Sim R B, Perry V H, Sim E
Abstract excerpt
Mannan-Binding lectin (MBL) is a serum lectin which can activate the classical complement pathway. Complement proteins of the classical pathway have been found in the brains of patients with Alzheimer's disease (AD) in association with AD brain pathology. To investigate the role for MBL in AD we have looked for its presence in the brain by immunohistochemistry and determined the levels of MBL in paired samples of...
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