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Article

Human variability and noncancer risk assessment--an analysis of the default uncertainty factor.

Regulatory toxicology and pharmacology : RTP - 1 Feb 1998

Renwick A G, Lazarus N R

Abstract excerpt

A 10-fold uncertainty factor is used for noncancer risk assessments to allow for possible interindividual differences between humans in the fate of the chemical in the body (kinetics) and target organ sensitivity (dynamics). Analysis of a database on the variability in each of these aspects is co...

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PMID: 9629592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9629592-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

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