Article
Recurrent herpes simplex virus-induced erythema multiforme: different HLA-DQB1 alleles associate with severe mucous membrane versus skin attacks.
Scandinavian journal of immunology - 1 May 1998
Malo A, Kämpgen E, Wank R
Abstract excerpt
In some individuals a local herpetic lesion precipitates a generalized inflammation of the skin, designated as erythema multiforme (EM). We determined the frequencies of the immune response genes of the HLA system by molecular HLA class II typing in 46 patients with EM and in many of their family...
Topics
- Alleles
- Erythema Multiforme
- Gene Frequency
- Genes, MHC Class II
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains
- HLA-DR Antigens
- HLA-DRB1 Chains
- Herpes Simplex
- Humans
- Mucous Membrane
- Phenotype
- Recurrence
- Simplexvirus
- Skin