Article
Class II major histocompatibility complex typing across the ethnic barrier in pemphigoid gestationis. A study in Mexicans.
International journal of dermatology - 1 Jan 1999
García-González E, Castro-Llamas J, Karchmer S, Zúñiga J, de Oca D M, Ambaz M, Bolaños R, Granados J
Abstract excerpt
BACKGROUND: Pemphigoid gestationis (PG), also called herpes gestationis, is a rare autoimmune disease of pregnancy or puerperium (estimated 1 out of 50,000 pregnancies among Caucasians). A previous series has demonstrated an association of PG with human leukocyte antigen (HLA)-DR3 or HLA-DR4 haplotypes. While these haplotypes are most commonly found in individuals of European ancestry, they have also been found...
Topics
- Adolescent
- Adult
- Female
- Fluorescent Antibody Technique, Direct
- Gene Frequency
- Genetic Predisposition to Disease
- Gestational Age
- Histocompatibility Antigens Class I
- Histocompatibility Antigens Class II
- Histocompatibility Testing
- Humans
- Mexico