Article
HLA-DRB1*01 allele and low plasma immunoglobulin G1 concentration may predispose to herpes-associated recurrent lymphocytic meningitis.
Human immunology - 1 Feb 2010
Kallio-Laine Katariina, Seppänen Mikko, Aittoniemi Janne, Kautiainen Hannu, Seppälä Ilkka, Valtonen Ville, Färkkilä Markus, Kalso Eija, Lokki Marja-Liisa
Abstract excerpt
Recurrent lymphocytic meningitis (RLM) is a rare illness caused mostly by herpes simplex virus type 2 (HSV-2). Predisposing factors are not known. Deficiencies in immunoglobulin (Ig) G subclasses 1 (IgG1) and 3 (IgG3) and complement protein C4 are associated with susceptibility to and persistence of bacterial and viral infections. Selected HLA and mannose-binding lectin (MBL) alleles have previously been...
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