Article
HLA DQB1*0301 allele is involved in the susceptibility to erythema multiforme.
The Journal of investigative dermatology - 1 Oct 1991
Khalil I, Lepage V, Douay C, Morin L, al-Daccak R, Wallach D, Binet O, Lemarchand F, Degos L, Hors J
Abstract excerpt
Erythema multiforme (EM) is an acute, episodic inflammatory disorder of the skin and mucous membranes of various etiology that could be related to immunologic hypersensitivity response. EM has been previously reported to be associated with serologically defined HLA-DRw53 and DQw3 antigens. In this report, we reevaluate the role of HLA class II alleles in EM manifestations. With use of the polymerase chain...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Erythema Multiforme
- Female
- Genetic Predisposition to Disease
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- Humans
