Significantly increased occurrence of HLA-DQB1*0301 allele in patients with ocular cicatricial pemphigoid.

doi:10.1111/1523-1747.ep12332352

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Article

Significantly increased occurrence of HLA-DQB1*0301 allele in patients with ocular cicatricial pemphigoid.

The Journal of investigative dermatology - 1 Feb 1997

Chan L S, Hammerberg C, Cooper K D

Abstract excerpt

To determine the immunogenetic characteristics of patients with immune-mediated subepithelial blistering diseases of mucous membranes, we performed HLA-typing for the class II MHC gene DQB1*0301 allele using a direct method. Genomic DNA extracted from Caucasian patients was amplified by polymeras...

Topics

Alleles
Autoantibodies
Basement Membrane
Blotting, Southern
Eye Diseases
HLA-DQ Antigens
HLA-DQ beta-Chains
Humans
Immunoblotting
Pemphigoid, Benign Mucous Membrane

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