Article
Significantly increased occurrence of HLA-DQB1*0301 allele in patients with ocular cicatricial pemphigoid.
The Journal of investigative dermatology - 1 Feb 1997
Chan L S, Hammerberg C, Cooper K D
Abstract excerpt
To determine the immunogenetic characteristics of patients with immune-mediated subepithelial blistering diseases of mucous membranes, we performed HLA-typing for the class II MHC gene DQB1*0301 allele using a direct method. Genomic DNA extracted from Caucasian patients was amplified by polymerase chain reaction using primer pairs specific for the DQB loci followed by Southern blotting with a...
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