Article
Vesicular transport of progeny parvovirus particles through ER and Golgi regulates maturation and cytolysis.
PLoS pathogens - 1 Sept 2013
Bär Séverine, Rommelaere Jean, Nüesch Jürg P F
Abstract excerpt
Progeny particles of non-enveloped lytic parvoviruses were previously shown to be actively transported to the cell periphery through vesicles in a gelsolin-dependent manner. This process involves rearrangement and destruction of actin filaments, while microtubules become protected throughout the infection. Here the focus is on the intracellular egress pathway, as well as its impact on the properties and release...
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