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Article

Relation of a common mutation in methylenetetrahydrofolate reductase to plasma homocysteine and early onset coronary artery disease.

Clinical biochemistry - 1 Mar 1998

Dunn J, Title L M, Bata I, Johnstone D E, Kirkland S A, O'Neill B J, Zayed E, MacDonald M C, Dempsey G, Nassar B

Abstract excerpt

OBJECTIVE: In the presence of low serum folate, mutant 5,20-methylenetetrahydrofolate reductase (MTHFR + [A223V/C677T]) in the homozygous state (+/+), may predispose to higher plasma homocysteine (tHct) levels and coronary artery disease (CAD). To determine the impact of this relationship on pred...

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Source

Identifiers

PMID: 9622772
DOI: 10.1016/s0009-9120(97)00165-3

Genes

CAD
MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9622772-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Relation of a common mutation in methylenetetrahydrofolate reductase to plasma homocysteine and early onset coronary artery disease.PMID 9622772Read ↗

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