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Article

Extracellular levels of dopamine and its metabolite 3,4-dihydroxy-phenylacetic acid measured by microdialysis in the corpus striatum of conscious AS/AGU mutant rats.

Neuroscience - 1 Jul 1998

Campbell J M, Gilmore D P, Russell D, Growney C A, Favor G, Weir J, Stone T W, Payne A P

Abstract excerpt

The AS/AGU rat is a mutant derived from the Albino Swiss (AS) strain. It is characterized by an ungainly, staggering gait, hind limb rigidity, whole body tremor and, in older animals, difficulty in initiating movement. As and AS/AGU males aged three, six and nine months (n=6 per group) were used to estimate the levels of dopamine and its metabolites in the extracellular fluid of the caudate-putamen. The results...

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PMID: 9622232
DOI: 10.1016/s0306-4522(98)00053-0

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