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Article

Genetic analysis of absB, a Streptomyces coelicolor locus involved in global antibiotic regulation.

Journal of bacteriology - 1 Jul 1992

Adamidis T, Champness W

Abstract excerpt

The filamentous soil bacterium Streptomyces coelicolor is known to produce four antibiotics which are genetically and structurally distinct. An extensive search for antibiotic regulatory mutants led to the discovery of absB mutants, which are antibiotic deficient but sporulation proficient. Genetic analysis of the absB mutants has resulted in definition of the absB locus at 5 o'clock on the genetic map. Multiple...

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Identifiers

PMID: 1624449
DOI: 10.1128/jb.174.14.4622-4628.1992
PMCID: PMC206257

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic analysis of absB, a Streptomyces coelicolor locus involved in global antibiotic regulation.PMID 1624449Read ↗

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Regulation of the Streptomyces coelicolor calcium-dependent antibiotic by absA, encoding a cluster-linked two-component system.Semantic proximity Read ↗

Transcriptional regulation of Streptomyces coelicolor pathway-specific antibiotic regulators by the absA and absB loci.Semantic proximity Read ↗

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SCO6992, a Protein with β-Glucuronidase Activity, Complements a Mutation at the absR Locus and Promotes Antibiotic Biosynthesis in Streptomyces coelicolor.Semantic proximity Read ↗

Induction of antimicrobial activities in heterologous streptomycetes using alleles of the Streptomyces coelicolor gene absA1.Semantic proximity Read ↗

Genome-wide transcriptome analysis reveals that a pleiotropic antibiotic regulator, AfsS, modulates nutritional stress response in Streptomyces coelicolor A3(2).Semantic proximity Read ↗

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