Article
Influence of the HLA class II polymorphism in chronic Chagas' disease.
Parasite immunology - 1 Apr 1998
Fernandez-Mestre M T, Layrisse Z, Montagnani S, Acquatella H, Catalioti F, Matos M, Balbas O, Makhatadze N, Dominguez E, Herrera F, Madrigal A
Abstract excerpt
Chagas' disease or American trypanosomiasis due to Trypanosoma cruzi has existed at least since the time of the Inca empire and contributes significantly to cardiovascular morbidity and mortality in several countries of this continent. Due to the fundamental role of human class II molecules polymorphic residues in the control of the immune response, a study was designed to define by DNA typing HLA class II...
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