Article
HLA-C(*)03 is a risk factor for cardiomyopathy in Chagas disease.
Human immunology - 1 Sept 2000
Layrisse Z, Fernandez M T, Montagnani S, Matos M, Balbas O, Herrera F, Colorado I A, Catalioti F, Acquatella H
Abstract excerpt
Previous studies have shown the effect of class 1 as detected by serology or class 2 HLA genes by oligotyping upon susceptibility or resistance to the cardiomyopathy that develops in approximately one third of the Trypanosoma cruzi chronically infected patients. Low and intermediate resolution DNA typing of class 1 alleles was performed in a sample of 113 serologically positive individuals with and without...
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