Article
Leptin receptor signal transduction: OBRa and OBRb of fa type.
Biochemical and biophysical research communications - 29 May 1998
Yamashita T, Murakami T, Otani S, Kuwajima M, Shima K
Abstract excerpt
We report herein the characterization of activities of signal transduction for three types of leptin receptors (OBRs) from rats, the OBRa, OBRb, and OBRb with fa mutation (OBRb-fa), by measurement of the levels of tyrosine phosphorylation of STAT3 (signal transducers and activators of transcription 3) and MAPK (mitogen-activated protein kinase), which are induced by leptin stimulation of CHO cells stably...
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