Article
Mechanisms of genomic imprinting.
Current opinion in genetics & development - 1 Apr 1999
Brannan C I, Bartolomei M S
Abstract excerpt
A small number of mammalian genes undergo the process of genomic imprinting whereby the expression level of the alleles of a gene depends upon their parental origin. In the past year, attention has focused on the mechanisms that determine parental-specific expression patterns. Many imprinted genes are located in conserved clusters and, although it is apparent that imprinting of adjacent genes is jointly...
Topics
- Alleles
- Angelman Syndrome
- Animals
- DNA Methylation
- Female
- Genomic Imprinting
- Insulin-Like Growth Factor II
- Male
- Multigene Family
- Muscle Proteins
- Prader-Willi Syndrome
- RNA, Long Noncoding
- RNA, Untranslated