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Article

Lung-specific expression in mice of a dominant negative mutant form of the p53 tumor suppressor protein.

The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society - 1 Apr 1998

Morris G F, Hoyle G W, Athas G B, Lei W H, Xu J, Morris C B, Friedman M

Abstract excerpt

Lung cancer is the most frequent cause of cancer deaths in the United States. A strong correlation exists between mutations in the gene encoding the p53 tumor suppressor protein and lung malignancies. Our goal is to prepare a transgenic mouse model with disrupted p53 function in the epithelial ce...

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PMID: 9610073

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9610073-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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