Article
Association of HLA-DRB1 alleles with status of antibodies to hepatitis B surface and e antigen.
Journal of medical virology - 1 Aug 2024
Li Xinze, Zhou Qiaomiao, Lu Zhe, Huang Renliang, Lin Dan, Xu Jing, Yu Xinhua, Li Xuexia
Abstract excerpt
Antigen presentation by HLA class II molecules to CD4+ T cells is an essential step for generating antibodies to hepatitis B antigens. In this study, we investigated the association between the HLA-DRB1 gene and the status of antibodies to hepatitis B surface and e antigens. Our results revealed a significant association between the status of anti-HBsAg and HLA-DRB1*04:03 (OR = 4.11, 95% CI = 1.50-10.84,...
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