Article
HLA genetic heterogeneity of hepatitis B vaccine response in hemodialyzed patients.
Kidney international. Supplement - 1 Jun 1993
Caillat-Zucman S, Gimenez J J, Albouze G, Lebkiri B, Naret C, Jungers P, Bach J F
Abstract excerpt
Major histocompatibility complex (MHC) determinants are critical to the induction or suppression of immune response and have been shown to control the ability to produce antibodies in response to protein antigen. Hepatitis B vaccine commonly fails among patients with renal failure, but genetic factors that modulate response to this vaccination are not yet characterized. The availability of HLA Class II genotyping...
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