Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The ACE I/D Polymorphism in US Adults: Limited Evidence of Association With Hypertension-Related Traits and Sex-Specific Effects by Race/Ethnicity

18 Oct 2011

Abstract excerpt

BACKGROUND: The insertion/deletion (I/D) variant (rs4646994) of the angiotensin I-converting enzyme (ACE) gene is one of the most studied polymorphisms in relation to blood pressure and essential hypertension in humans. The evidence to date, however, on an association of this variant with blood pressure-related outcomes has been inconclusive. METHODS: We examined 5,561 participants of the Third National Health...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Associations and Epidemiology
Share to Genetics and Physical Performance

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Renin-Angiotensin System Studies

Source

Identifiers

PMID: 21993364
DOI: 10.1038/ajh.2011.182

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 18 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The ACE I/D Polymorphism in US Adults: Limited Evidence of Association With Hypertension-Related Traits and Sex-Specific Effects by Race/EthnicityPMID 21993364Read ↗

Association Between ACE (I/D) Polymorphism and Essential Hypertension (EH): An Updated Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Angiotensin-converting enzyme insertion/deletion polymorphism contributes high risk for chronic kidney disease in Asian male with hypertension--a meta-regression analysis of 98 observational studies.Semantic proximity Read ↗

Smoking-dependent effects of the angiotensin-converting enzyme gene insertion/deletion polymorphism on blood pressure.Semantic proximity Read ↗

A population study of ethnic variations in the angiotensin-converting enzyme I/D polymorphismSemantic proximity Read ↗

Sex-specific effects of ACE I/D and AGT-M235T on pulse pressure: the HyperGEN Study.Semantic proximity Read ↗

Association between angiotensin-converting enzyme insertion/deletion polymorphisms and the risk of heart disease: an updated meta-analysis.Semantic proximity Read ↗

Angiotensin converting enzyme genetic polymorphism is not associated with hypertension in a cross-sectional sample of a Japanese population: the Shibata Study.Semantic proximity Read ↗

Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham Heart Study.Semantic proximity Read ↗

Racial difference in the relationship of an angiotensin I-converting enzyme gene polymorphism to serum angiotensin I-converting enzyme activity.Semantic proximity Read ↗

Association between the <i>ACE</i> I/D gene polymorphism and progressive renal failure in autosomal dominant polycystic kidney disease: A meta-analysisSemantic proximity Read ↗

Female Sex and Angiotensin-Converting Enzyme (ACE) Insertion/Deletion Polymorphism Amplify the Effects of Adiposity on Blood Pressure.Semantic proximity Read ↗

Angiotensin Converting Enzyme (ACE) Gene I/D Polymorphism Is Significantly Associated with Insulin Resistance and Polycystic Ovary Syndrome: A Meta-Analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.