Mutation, selection, and memory in B lymphocytes of exothermic vertebrates.

doi:10.1111/j.1600-065x.1998.tb01426.x

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Article

Mutation, selection, and memory in B lymphocytes of exothermic vertebrates.

Immunological reviews - 1 Apr 1998

Hsu E

Abstract excerpt

Unlike mammals, cold-blooded vertebrates produce antibodies of low heterogeneity that show little increase in binding affinity with time after immunization. In secondary responses, antibody titers and affinities are often little, if any, higher than in primary responses. That is, specificity, div...

Topics

Alleles
Animals
B-Lymphocytes
Base Sequence
Body Temperature Regulation
Genes, Immunoglobulin
Immunologic Memory
Molecular Sequence Data
Mutation
Selection, Genetic

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