Article
The first strand transfer during HIV-1 reverse transcription can occur either intramolecularly or intermolecularly.
Virology - 10 May 1998
van Wamel J L, Berkhout B
Abstract excerpt
Reverse transcription is a complicated process that involves at least two cDNA transfer reactions to produce a full-length copy DNA of the retroviral RNA genome. Because one retrovirus particle contains two identical genomic RNA molecules, the transfers can occur in an intramolecular or intermole...
Topics
- Base Sequence
- Cell Line
- DNA, Complementary
- DNA, Viral
- Genome, Viral
- HIV-1
- Humans
- Mutation
- Plasmids
- Polymerase Chain Reaction
- Transcription, Genetic
- Transfection