Article
HIV-1 reverse transcription.
Cold Spring Harbor perspectives in medicine - 1 Oct 2012
Hu Wei-Shau, Hughes Stephen H
Abstract excerpt
Reverse transcription and integration are the defining features of the Retroviridae; the common name "retrovirus" derives from the fact that these viruses use a virally encoded enzyme, reverse transcriptase (RT), to convert their RNA genomes into DNA. Reverse transcription is an essential step in retroviral replication. This article presents an overview of reverse transcription, briefly describes the structure...
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