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Article

The association between telomerase, p53, and clinical staging in colorectal cancer.

American journal of surgery - 1 May 1998

Brown T, Aldous W, Lance R, Blaser J, Baker T, Williard W

Abstract excerpt

BACKGROUND: A proposed etiology of tumor activation involves p53 mutations while telomerase may serve as a key enzyme for maintenance of tumor cell proliferation. METHODS: Telomerase activity levels were measured in colorectal adenocarcinomas and corresponding normal tissue using a modified telomeric repeat amplification protocol, and p53 mutations were identified using immunohistochemical staining. Results were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9600278
DOI: 10.1016/s0002-9610(98)00057-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Semantic proximity does not establish scientific evidence.

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The association between telomerase, p53, and clinical staging in colorectal cancer.PMID 9600278Read ↗

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Correlation between malignancy grade and p53 gene in relation to thymidine phosphorylase activity in colorectal cancer patients.Semantic proximity Read ↗

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