Article
Telomerase activation in colorectal carcinogenesis.
The Journal of pathology - 1 Oct 1999
Yan P, Saraga E P, Bouzourene H, Bosman F T, Benhattar J
Abstract excerpt
Telomerase activity has been detected in germ cells as well as in the developing embryo. Activity is no longer detectable in most somatic cells of the neonate, although low levels of activity persist in regenerative tissues. Telomerase has been found to be reactivated or up-regulated in the majority of cancers. The colorectal adenoma-carcinoma sequence is one of the best-characterized models of multistep...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
