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Article

Telomerase activity and p53 gene mutation in familial polyposis coli.

Anticancer research - 1 Jan 2000

Ikeguchi M, Makino M, Kaibara N

Abstract excerpt

BACKGROUND: Familial adenomatous polyposis (FAP) is a dominantly inherited disorder and it is difficult to know when polyps change to carcinoma. In this study, we retrospectively evaluated whether telomerase activity and p53 gene mutations are useful parameters for detecting malignant changes in...

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Source

Identifiers

PMID: 11268463

Genes

FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11268463-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Telomerase activity and p53 gene mutation in familial polyposis coli.PMID 11268463Read ↗

Telomerase activation in colorectal carcinogenesis.Semantic proximity Read ↗

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p53 gene mutations in colorectal tumors from patients with familial polyposis coli.Semantic proximity Read ↗

No evidence for overexpression of the p53 protein and mutations in exons 4-9 of the p53 gene in a large family with adenomatous polyposis.Semantic proximity Read ↗

The association between telomerase, p53, and clinical staging in colorectal cancer.Semantic proximity Read ↗

Familial Adenomatous PolyposisSemantic proximity Read ↗

Detailed analysis of genetic alterations in colorectal tumors from patients with and without familial adenomatous polyposis (FAP).Semantic proximity Read ↗

Hereditary Colorectal Cancer Syndromes: Molecular Genetics and Precision MedicineSemantic proximity Read ↗

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