Article
Engineered resistance in Aedes aegypti to a West African and a South American strain of yellow fever virus.
1 May 1998
Abstract excerpt
Double subgenomic Sindbis (dsSIN) viruses were engineered to transduce mosquito cells with antisense RNA derived either from the premembrane (prM) or polymerase (NS5) coding regions of the 17D vaccine strain of yellow fever virus (YFV). Aedes albopictus C6/36 cells were infected at high multiplicities of infection (MOI) with each dsSIN virus. Forty-eight hours later, the transduced cells were challenged with an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
