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Article

Synthetic miRNAs induce dual arboviral-resistance phenotypes in the vector mosquito Aedes aegypti

1 Feb 2018

Abstract excerpt

Abstract Mosquito-borne arboviruses are responsible for recent dengue, chikungunya, and Zika pandemics. The yellow-fever mosquito,Aedes aegypti, plays an important role in the transmission of all three viruses. We developed a miRNA-based approach that results in a dual resistance phenotype in mosquitoes to dengue serotype 3 (DENV-3) and chikungunya (CHIKV) viruses. The target viruses are from two distinct...

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PMID: 30271898
DOI: 10.1038/s42003-017-0011-5

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