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Article

Sindbis virus‐induced silencing of dengue viruses in mosquitoes

1 Jun 2001

Abstract excerpt

Aedes aegypti were injected intrathoracically with double subgenomic Sindbis (dsSIN) viruses with inserted sequences derived from the genome of one or more of the four dengue (DEN) virus serotypes. Mosquitoes were highly resistant to challenge with homologous DEN viruses from which the effector sequences were derived, and resistance to DEN viruses was independent of the orientation of the effector RNA. dsSIN...

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PMID: 11437918
DOI: 10.1046/j.1365-2583.2001.00267.x

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