[New phenotypic manifestation of the ad2 mutation in Saccharomyces cerevisiae yeast--the inability to grow on a synthetic medium with glycerol and hypoxanthine].

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Article

[New phenotypic manifestation of the ad2 mutation in Saccharomyces cerevisiae yeast--the inability to grow on a synthetic medium with glycerol and hypoxanthine].

Genetika - 1 Feb 1998

Zekhnov A M, Andreĭchuk Iu V, Domkin V D

Abstract excerpt

The ADE2 gene of Saccharomyces cerevisiae yeast encodes aminoimidazole ribonucleotide-carboxylase (AIR-carboxylase), an enzyme catalyzing the sixth stage of purine nucleotide biosynthesis. Strains bearing the ade2 mutation are able to grow on a glucose-containing synthetic medium with the addition of adenine or hypoxanthine, which under the action of the cellular phosphoribosyltransferases are converted into...

Topics

Carboxy-Lyases
Culture Media
Genes, Fungal
Genetic Code
Genotype
Glycerol
Hypoxanthine
Mutation
Phenotype
Purines
Saccharomyces cerevisiae

Source

Open in PubMed

Identifiers

PMID: 9589850

Provenance

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