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Article

Osteoblast-like cells from human subchondral osteoarthritic bone demonstrate an altered phenotype in vitro: possible role in subchondral bone sclerosis.

Arthritis and rheumatism - 1 May 1998

Hilal G, Martel-Pelletier J, Pelletier J P, Ranger P, Lajeunesse D

Abstract excerpt

OBJECTIVE: Osteoarthritis (OA) is accompanied by subchondral bone sclerosis. The present study was undertaken to determine whether osteoblast-like cells in patients with OA show an abnormal phenotype that could contribute to this sclerosis. METHODS: Explants and primary in vitro osteoblast-like cell cultures were prepared from subchondral bone specimens from OA patients or from bone removed at autopsy from...

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PMID: 9588742
DOI: 10.1002/1529-0131(199805)41:5<891::AID-ART17>3.0.CO;2-X

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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