Article
Equivalent osteoblastic differentiation function of human mesenchymal stem cells from rheumatoid arthritis in comparison with osteoarthritis.
Rheumatology (Oxford, England) - 1 Jun 2009
Morimoto Daiki, Kuroda Shoko, Kizawa Takuji, Nomura Koji, Higuchi Chikahisa, Yoshikawa Hideki, Tomita Tetsuya
Abstract excerpt
OBJECTIVE: To evaluate the osteoblastic differentiation of human mesenchymal stem cells (hMSCs) in patients with RA. METHODS: Heparinized bone marrow aspirate was obtained from patients with OA and RA. Mononuclear cells were cultured for 2 weeks and a colony-forming assay was performed. The phenotype of cells was analysed by flow cytometry. Passage 2 cells were cultured with beta-glycerophosphate (bGP) in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
