Article
Molecular and cellular basis of radiation fibrosis.
International journal of radiation biology - 1 Apr 1998
Burger A, Löffler H, Bamberg M, Rodemann H P
Abstract excerpt
PURPOSE: Recent data from the literature and the experimental work of the authors clearly indicate that TGF-beta1 is a key modulator of cellular events, for example, induction of terminal differentiation, resulting in radiation-induced fibrosis. Therefore, the present study analysed which cellula...
Topics
- Animals
- Antibodies
- Cell Differentiation
- Colony-Forming Units Assay
- Fibroblasts
- Humans
- Lung
- Phenotype
- Radiation Pneumonitis
- Rats
- Stem Cells
- Transforming Growth Factor beta