Article
Molecular and cellular basis of radiation fibrosis.
International journal of radiation biology - 1 Apr 1998
Burger A, Löffler H, Bamberg M, Rodemann H P
Abstract excerpt
PURPOSE: Recent data from the literature and the experimental work of the authors clearly indicate that TGF-beta1 is a key modulator of cellular events, for example, induction of terminal differentiation, resulting in radiation-induced fibrosis. Therefore, the present study analysed which cellular processes induced by exogenously added TGF-beta could be responsible for the induction, development and manifestation...
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