Abnormal phenotype of cultured fibroblasts in human skin with chronic radiotherapy damage.

doi:10.1016/s0167-8140(97)00195-3

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Article

Abnormal phenotype of cultured fibroblasts in human skin with chronic radiotherapy damage.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Jun 1998

Delanian S, Martin M, Bravard A, Luccioni C, Lefaix J L

Abstract excerpt

PURPOSE: The pathophysiological aspects of radiation-induced fibrosis (RIF) have not been well characterized. We therefore cultured human fibroblasts from samples of skin with RIF to investigate the long-term effects of therapeutic irradiation. MATERIALS AND METHODS: Biopsies of normal and RIF sk...

Topics

Adult
Aged
Biopsy
Blotting, Northern
Breast Neoplasms
Catalase
Cell Division
Cell Survival
Cells, Cultured
Chronic Disease
DNA Probes
Dose-Response Relationship, Radiation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Female

Fibroblasts

Follow-Up Studies

Head and Neck Neoplasms

Humans

Male

Source

Open in PubMed

Identifiers

PMID: 9681888
DOI: 10.1016/s0167-8140(97)00195-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9681888-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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