Article
TGF-beta1-mediated alterations of rat lung fibroblast differentiation resulting in the radiation-induced fibrotic phenotype.
International journal of radiation biology - 1 Apr 2000
Hakenjos L, Bamberg M, Rodemann H P
Abstract excerpt
PURPOSE: To study the influence of TGF-beta1 and TGF-beta-neutralizing antibodies on the clonogenic activity and terminal differentiation of rat lung fibroblasts following radiation exposure. MATERIAL AND METHODS: Early passage rat lung fibroblasts were used in this study. Colony formation assays were applied to determine the radiation sensitivity as well as radiation-induced alterations in differentiation...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
