Article
Evidence for autosomal dominant inheritance of prostate cancer.
American journal of human genetics - 1 Jun 1998
Schaid D J, McDonnell S K, Blute M L, Thibodeau S N
Abstract excerpt
A family-history cancer survey was conducted on 5,486 men who underwent a radical prostatectomy, for clinically localized prostate cancer, in the Department of Urology at the Mayo Clinic during 1966-95; 4,288 men responded to the survey. Complex segregation analysis was performed to assess the genetic basis of age at diagnosis and the familial clustering of prostate cancer. For the total group, no single-gene...
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