Genetic susceptibility to prostate cancer: a review.

Abstract excerpt

A genetic component in prostate cancer has been recognized since decades. Through numerous epidemiological and molecular biological studies, much evidence has accumulated in favor of a significant but heterogeneous hereditary component in prostate cancer (PCa) susceptibility. Since the mapping of a high-penetrant PCa susceptibility locus at 1q24-25, much attention has been paid to the identification of PCa...

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