Article
Uncertainty in the diagnosis of cystic fibrosis: possible role of in vivo nasal potential difference measurements.
The Journal of pediatrics - 1 Apr 1998
Wilson D C, Ellis L, Zielenski J, Corey M, Ip W F, Tsui L C, Tullis E, Knowles M R, Durie P R
Abstract excerpt
The diagnosis of cystic fibrosis (CF) is not always certain, despite extensive clinical evaluation, multiple sweat chloride tests, and genotype analysis. We hypothesized that nasal transepithelial potential difference measurements have a useful role in this situation. In 11 patients without an established diagnosis of CF, results of simultaneous nasal potential difference (PD) and sweat chloride measurements were...
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