Article
Nasal potential difference measurements in patients with atypical cystic fibrosis.
The European respiratory journal - 1 Jun 2001
Wilschanski M, Famini H, Strauss-Liviatan N, Rivlin J, Blau H, Bibi H, Bentur L, Yahav Y, Springer H, Kramer M R, Klar A, Ilani A, Kerem B, Kerem E
Abstract excerpt
The diagnosis of cystic fibrosis (CF) is based on characteristic clinical and laboratory findings. However, a subgroup of patients present with an atypical phenotype that comprises partial CF phenotype, borderline sweat tests and one or even no common cystic fibrosis transmembrane conductance regulator (CFTR) mutations. The aim of this study was to evaluate the role of nasal potential difference (PD) measurements...
Topics
- Adolescent
- Adult
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- Female
- Genotype
- Humans
- Male
- Membrane Potentials
- Nasal Mucosa
- Phenotype
- Predictive Value of Tests
- Reference Values