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Article

Does integration of various ion channel measurements improve diagnostic performance in cystic fibrosis?

Annals of the American Thoracic Society - 1 May 2014

Ooi Chee Y, Dupuis Annie, Gonska Tanja, Ellis Lynda, Ni Andy, Jarvi Keith, Martin Sheelagh, Ray Peter, Steele Leslie, Kortan Paul, Dorfman Ruslan, Solomon Melinda, Zielenski Julian, Corey Mary, Tullis Elizabeth, Durie Peter

Abstract excerpt

RATIONALE: The diagnosis of cystic fibrosis (CF) may remain inconclusive despite comprehensive evaluation. OBJECTIVES: Determine whether combined ion channel measurements (C-ICMs) obtained from different end-organ epithelia can help diagnose CF. METHODS: Prospective enrollment of (1) a training sample of 156 non-CF subjects and 107 patients with CF, and (2) a validation cohort of 202 patients with single-organ...

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Identifiers

PMID: 24697796
DOI: 10.1513/AnnalsATS.201311-412OC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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