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Article

Increased invasiveness ofMUCI1 cDNA-transfected human gastric cancer MKN74 cells

4 May 1998

Abstract excerpt

MUC1 mucin is an anti-adhesion molecule expressed in a wide variety of tumors. To examine whether MUC1 mucin is involved in tumor invasion, we have prepared MUC1 transfectants using the human gastric cancer cell line MKN74 and performed an in vivo tumor assay by transplanting these into nude mice. Tumor weight at 71 days after s.c. injection of transfectants was measured, showing that the in vivo growth of MUC1...

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PMID: 9579575
DOI: 10.1002/(sici)1097-0215(19980504)76:3<377::aid-ijc15>3.0.co;2-8

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