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Article

Heterogeneity of MUC1 expression by human breast carcinoma cell lines in vivo and in vitro.

Breast cancer research and treatment - 1 Dec 1999

Walsh M D, Luckie S M, Cummings M C, Antalis T M, McGuckin M A

Abstract excerpt

Increased expression of the epithelial mucin MUC1 has been linked to tumor aggressiveness in human breast carcinoma. Recent studies have demonstrated that overexpression of MUC1 interferes with cell-substrate and cell-cell adhesion by masking cell surface integrins and E-cadherin. Additionally, the cytoplasmic tail of MUC1 is involved in signal transduction and interactions with catenins. In the present study, we...

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Source

Identifiers

PMID: 10718487
DOI: 10.1023/a:1006345301364

Genes

MUC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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